Feature: for medium temperatures > °C or frequent changes in temperature. 0 to 1 bar – 0 to 60 bar relative, 0 to 1 bar – 0 to 25 bar absolute; Medium. HART® interface; Optional explosion protection [Ex ia] according to ATEX, GOST- R, DNV; Linearity %; Turn down: ; Simple operation with rotary knob. Get this from a library! Farmacevtska tehnologija. Del 1, Praktikum. [Julijana Kristl ; Jelka Šmid-Korbar; Stanko Srčič].
|Published (Last):||16 October 2009|
|PDF File Size:||8.86 Mb|
|ePub File Size:||4.9 Mb|
|Price:||Free* [*Free Regsitration Required]|
Pellet coating is commonly performed in a fluid bed coater such as a Wurster coater.
Farmacevtska tehnologija: Praktikum. Del 1
Farmacevtska tehnologija: za studii i praktika – Angel Simov – Google Books
Granule shape was affected by interplay of binder content, binder particle size and granulation time. Besides the nature and amount of binder, the mechanism of agglomerate formation seems to have an impact on drug dissolution rate.
Granule size was mainly influenced by binder particle size. Solid state analysis confirmed unaltered physical state of the granulate components and the absenceof interactions between the active and excipients.
Experimentally, the draft tube two-phase flow was evaluated by measuring the volume fraction of pellets within the draft tube and local particle velocities at the tube exit and by monitoring the local pressure drop fluctuations. The aim of this study was to investigate the influence of binder content, binder particle size, granulation time and inlet air flow rate on granule sizeand size distribution, granule shape and flowability, as well as on drug release rate.